Wharton's Jelly-Derived Mesenchymal Stromal Cells and Fibroblast-Derived Extracellular Matrix Synergistically Activate Apoptosis in a p21-Dependent Mechanism in WHCO1 and MDA MB 231 Cancer Cells In Vitro

The tumour microenvironment plays a crucial role in tumour progression and comprises tumour stroma which is made up of different cell types and the extracellular matrix (ECM). Mesenchymal stromal cells (MSCs) are part of the tumour stroma and may have conflicting effects on tumour growth. In this st...

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Vydáno v:Stem Cells Int
Hlavní autoři: Dzobo, Kevin, Vogelsang, Matjaz, Thomford, Nicholas E., Dandara, Collet, Kallmeyer, Karlien, Pepper, Michael S., Parker, M. Iqbal
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737007/
https://ncbi.nlm.nih.gov/pubmed/26880967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4842134
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