Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

Several newly generated mouse embryonic stem (ES) cell lines were tested for their ability to produce completely ES cell-derived mice at early passage numbers by ES cell <==> tetraploid embryo aggregation. One line, designated R1, produced live offspring which were completely ES cell-derived as judg...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Nagy, A, Rossant, J, Nagy, R, Abramow-Newerly, W, Roder, J C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47369/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8378314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.18.8424
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