Загрузка...

Low oxygen tension reverses antineoplastic effect of iron chelator deferasirox in human glioblastoma cells

BACKGROUND: Overcoming resistance to treatment is an essential issue in many cancers including glioblastoma (GBM), the deadliest primary tumor of the central nervous system. As dependence on iron is a key feature of tumor cells, using chelators to reduce iron represents an opportunity to improve con...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :BMC Cancer
Главные авторы: Legendre, Claire, Avril, Sylvie, Guillet, Catherine, Garcion, Emmanuel
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736662/
https://ncbi.nlm.nih.gov/pubmed/26832741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2074-y
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!