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Low oxygen tension reverses antineoplastic effect of iron chelator deferasirox in human glioblastoma cells
BACKGROUND: Overcoming resistance to treatment is an essential issue in many cancers including glioblastoma (GBM), the deadliest primary tumor of the central nervous system. As dependence on iron is a key feature of tumor cells, using chelators to reduce iron represents an opportunity to improve con...
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| Gepubliceerd in: | BMC Cancer |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4736662/ https://ncbi.nlm.nih.gov/pubmed/26832741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2074-y |
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