Two-stage Genome-wide Methylation Profiling in Childhood-onset Crohn's Disease Implicates Epigenetic Alterations at the VMP1/MIR21 and HLA Loci

BACKGROUND: As a result of technological and analytical advances, genome-wide characterization of key epigenetic alterations is now feasible in complex diseases. We hypothesized that this may provide important insights into gene-environmental interactions in Crohn's disease (CD) and is especial...

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Bibliografische gegevens
Gepubliceerd in:Inflamm Bowel Dis
Hoofdauteurs: Adams, Alex T., Kennedy, Nicholas A., Hansen, Richard, Ventham, Nicholas T., O'Leary, Kate R., Drummond, Hazel E., Noble, Colin L., El-Omar, Emad, Russell, Richard K., Wilson, David C., Nimmo, Elaine R., Hold, Georgina L., Satsangi, Jack
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Lippincott Williams & Wilkins 2014
Onderwerpen:
Original Basic Science Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736293/
https://ncbi.nlm.nih.gov/pubmed/25144570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000179
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