HSP60 plays a regulatory role in IL-1β-induced microglial inflammation via TLR4-p38 MAPK axis

BACKGROUND: IL-1β, also known as “the master regulator of inflammation”, is a potent pro-inflammatory cytokine secreted by activated microglia in response to pathogenic invasions or neurodegeneration. It initiates a vicious cycle of inflammation and orchestrates various molecular mechanisms involved...

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Détails bibliographiques
Publié dans:J Neuroinflammation
Auteurs principaux: Swaroop, Shalini, Sengupta, Nabonita, Suryawanshi, Amol Ratnakar, Adlakha, Yogita K, Basu, Anirban
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736186/
https://ncbi.nlm.nih.gov/pubmed/26838598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0486-x
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