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Colorectal Delivery and Retention of PEG-Amprenavir-Bac7 Nanoconjugates - Proof of Concept for HIV Mucosal Pre-Exposure Prophylaxis
Local delivery of anti-HIV drugs to the colorectal mucosa, a major site of HIV replication, and their retention within mucosal tissue would allow for a reduction in dose administered, reduced dosing frequency and minimal systemic exposure. The current report describes a mucosal Pre-Exposure Prophyla...
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Publicado no: | Drug Deliv Transl Res |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4736156/ https://ncbi.nlm.nih.gov/pubmed/26712122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-015-0269-4 |
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