Longitudinal metabolic imaging of hepatocellular carcinoma in transgenic mouse models identifies acylcarnitine as a potential biomarker for early detection

The cumulative effects of hepatic injury due to hepatitis B virus (HBV) infections and aflatoxin-B(1) (AFB(1)) exposure are the major risk factors of HCC. Understanding early metabolic changes involving these risk factors in an animal model closely resembling human hepatocellular carcinoma (HCC) is...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Yaligar, Jadegoud, Teoh, Wei Wei., Othman, Rashidah, Verma, Sanjay Kumar, Phang, Beng Hooi, Lee, Swee Shean, Wang, Who Whong, Toh, Han Chong, Gopalan, Venkatesh, Sabapathy, Kanaga, Velan, S. Sendhil
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735819/
https://ncbi.nlm.nih.gov/pubmed/26831370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20299
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