α-tomatine inhibits growth and induces apoptosis in HL-60 human myeloid leukemia cells

α-tomatine is a glycoalkaloid that occurs naturally in tomatoes (Lycopersicon esculentum). In the present study, the effects of α-tomatine on human myeloid leukemia HL-60 cells were investigated. Treatment of HL-60 cells with α-tomatine resulted in growth inhibition and apoptosis in a concentration-...

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Udgivet i:Mol Med Rep
Main Authors: HUANG, HUARONG, CHEN, SHAOHUA, VAN DOREN, JEREMIAH, LI, DONGLI, FARICHON, CHELSEA, HE, YAN, ZHANG, QIUYAN, ZHANG, KUN, CONNEY, ALLAN H, GOODIN, SUSAN, DU, ZHIYUN, ZHENG, XI
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735690/
https://ncbi.nlm.nih.gov/pubmed/25625536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.3238
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