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Quantitative phospho-proteomics reveals the Plasmodium merozoite triggers pre-invasion host kinase modification of the red cell cytoskeleton

The invasive blood-stage malaria parasite – the merozoite – induces rapid morphological changes to the target erythrocyte during entry. However, evidence for active molecular changes in the host cell that accompany merozoite invasion is lacking. Here, we use invasion inhibition assays, erythrocyte r...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Zuccala, Elizabeth S., Satchwell, Timothy J., Angrisano, Fiona, Tan, Yan Hong, Wilson, Marieangela C., Heesom, Kate J., Baum, Jake
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735681/
https://ncbi.nlm.nih.gov/pubmed/26830761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19766
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