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OGR1/GPR68 Modulates the Severity of Experimental Autoimmune Encephalomyelitis and Regulates Nitric Oxide Production by Macrophages

Ovarian cancer G protein-coupled receptor 1 (OGR1) is a proton-sensing molecule that can detect decreases in extracellular pH that occur during inflammation. Although OGR1 has been shown to have pro-inflammatory functions in various diseases, its role in autoimmunity has not been examined. We theref...

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Publicado en:PLoS One
Autores principales: D’Souza, Cheryl A., Zhao, Fei Linda, Li, Xujian, Xu, Yan, Dunn, Shannon E., Zhang, Li
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735495/
https://ncbi.nlm.nih.gov/pubmed/26828924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148439
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