The Role of NADPH Oxidases (NOXs) in Liver Fibrosis and the Activation of Myofibroblasts

Chronic liver injury, resulted from different etiologies (e.g., virus infection, alcohol abuse, nonalcoholic steatohepatitis (NASH) and cholestasis) can lead to liver fibrosis characterized by the excess accumulation of extracellular matrix (ECM) proteins (e.g., type I collagen). Hepatic myofibrobla...

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Bibliographic Details
Published in:Front Physiol
Main Authors: Liang, Shuang, Kisseleva, Tatiana, Brenner, David A.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735448/
https://ncbi.nlm.nih.gov/pubmed/26869935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00017
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