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ATTIRE: Albumin To prevenT Infection in chronic liveR failurE: study protocol for a single-arm feasibility trial

INTRODUCTION: Circulating prostaglandin E(2) levels are elevated in acutely decompensated cirrhosis and have been shown to contribute to immune suppression. Albumin binds and inactivates this hormone. Human albumin solution could thus be repurposed as an immune restorative drug in these patients. Th...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: China, Louise, Muirhead, Nicola, Skene, Simon S, Shabir, Zainib, PH De Maeyer, Roel, Maini, Alexander AN, W Gilroy, Derek, J O'Brien, Alastair
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735307/
https://ncbi.nlm.nih.gov/pubmed/26810999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2015-010132
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