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Investigating the Consequences of Interference between Multiple CD8(+) T Cell Escape Mutations in Early HIV Infection

During early human immunodeficiency virus (HIV) infection multiple CD8(+) T cell responses are elicited almost simultaneously. These responses exert strong selective pressures on different parts of HIV’s genome, and select for mutations that escape recognition and are thus beneficial to the virus. S...

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Publicat a:PLoS Comput Biol
Autors principals: Garcia, Victor, Feldman, Marcus W., Regoes, Roland R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735108/
https://ncbi.nlm.nih.gov/pubmed/26829720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004721
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