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External signals shape the epigenome

A new study shows how a single cytokine, interleukin-4, regulates hematopoietic lineage choice by activating the JAK3–STAT6 pathway, which causes dendritic-cell-specific DNA demethylation. Please see related Research article: http://www.genomebiology.com/2016/17/1/4

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Bibliografiske detaljer
Udgivet i:Genome Biol
Hovedforfatter: Lennartsson, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734871/
https://ncbi.nlm.nih.gov/pubmed/26829670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0884-5
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