Biomarkers predicting resistance to epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer with wild-type KRAS

EGFR pathway is an important therapeutic target in human tumors, including metastatic colorectal cancer (mCRC). The advent of EGFR-targeted monoclonal antibodies panitumumab and cetuximab has generated promise for the treatment of mCRC and has largely improved patients’ progression-free survival (PF...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Onco Targets Ther
Päätekijät: Liu, Jiang, Hu, Jing, Cheng, Lei, Ren, Wei, Yang, Mi, Liu, Baorui, Xie, Li, Qian, Xiaoping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove Medical Press 2016
Aiheet:
Review
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734822/
https://ncbi.nlm.nih.gov/pubmed/26869800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S86966
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