Neuropathogenicity of Two Saffold Virus Type 3 Isolates in Mouse Models

OBJECTIVE: Saffold virus (SAFV), a picornavirus, is occasionally detected in children with acute flaccid paralysis, meningitis, and cerebellitis; however, the neuropathogenicity of SAFV remains undetermined. METHODS: The virulence of two clinical isolates of SAFV type 3 (SAFV-3) obtained from a pati...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kotani, Osamu, Naeem, Asif, Suzuki, Tadaki, Iwata-Yoshikawa, Naoko, Sato, Yuko, Nakajima, Noriko, Hosomi, Takushi, Tsukagoshi, Hiroyuki, Kozawa, Kunihisa, Hasegawa, Hideki, Taguchi, Fumihiro, Shimizu, Hiroyuki, Nagata, Noriyo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734772/
https://ncbi.nlm.nih.gov/pubmed/26828718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148184
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