In vitro stress effect on degradation and drug release behaviors of basic fibroblast growth factor – poly(lactic-co-glycolic-acid) microsphere

OBJECTIVE: To study the degradation and basic fibroblast growth factor (bFGF) release activity of bFGF – poly(lactic-co-glycolic-acid) microsphere (bFGF-PLGA MS) under stress in vitro, including the static pressure and shearing force-simulating mechanical environment of the joint cavity. METHOD: Fir...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Xiong, Yan, Yu, Zeping, Lang, Yun, Hu, Juanyu, Li, Hong, Yan, Yonggang, Tu, Chongqi, Yang, Tianfu, Song, Yueming, Duan, Hong, Pei, Fuxing
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734730/
https://ncbi.nlm.nih.gov/pubmed/26869764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S93554
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