Formulation, optimization, and pharmacodynamic evaluation of chitosan/phospholipid/β-cyclodextrin microspheres

Cholinergic neurotransmission loss is the main cause of cognitive impairment in patients with Alzheimer’s disease. Phospholipids (PLs) play an essential role in memory and learning abilities. Moreover, PLs act as a source of choline in acetylcholine synthesis. This study aimed to prepare and optimiz...

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Bibliographic Details
Published in:Drug Des Devel Ther
Main Authors: Shan, Lu, Tao, En-Xue, Meng, Qing-Hui, Hou, Wen-Xia, Liu, Kang, Shang, Hong-Cai, Tang, Jin-Bao, Zhang, Wei-Fen
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734723/
https://ncbi.nlm.nih.gov/pubmed/26869763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S97982
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