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Nanoparticle-Mediated Intracellular Delivery Enables Cryopreservation of Human Adipose-Derived Stem Cells Using Trehalose as the Sole Cryoprotectant

In this study, pH responsive genipin-crosslinked Pluronic F127-chitosan nanoparticles (GNPs) was synthesized to encapsulate trehalose for intracellular delivery to cryopreserve primary human adipose-derived stem cells (hADSCs). Trehalose is a disaccharide of glucose used by lower-organisms to surviv...

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Dades bibliogràfiques
Publicat a:ACS Appl Mater Interfaces
Autors principals: Rao, Wei, Huang, Haishui, Wang, Hai, Zhao, Shuting, Dumbleton, Jenna, Zhao, Gang, He, Xiaoming
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734639/
https://ncbi.nlm.nih.gov/pubmed/25679454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsami.5b00655
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