One-step multiplex real-time RT-PCR assay for detecting and genotyping wild-type group A rotavirus strains and vaccine strains (Rotarix® and RotaTeq®) in stool samples

Background. Group A rotavirus (RVA) infection is the major cause of acute gastroenteritis (AGE) in young children worldwide. Introduction of two live-attenuated rotavirus vaccines, RotaTeq® and Rotarix®, has dramatically reduced RVA associated AGE and mortality in developed as well as in many develo...

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Vydáno v:PeerJ
Hlavní autoři: Gautam, Rashi, Mijatovic-Rustempasic, Slavica, Esona, Mathew D., Tam, Ka Ian, Quaye, Osbourne, Bowen, Michael D.
Médium: Artigo
Jazyk:Inglês
Vydáno: PeerJ Inc. 2016
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734446/
https://ncbi.nlm.nih.gov/pubmed/26839745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.1560
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