Mechanism of neem limonoids-induced cell death in cancer: role of oxidative phosphorylation

We have previously reported that neem limonoids (neem) induce multiple cancer cell death pathways. Here we dissect the underlying mechanisms of neem-induced apoptotic cell death in cancer. We observed that neem-induced caspase activation does not require Bax/Bak channel-mediated mitochondrial outer...

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Udgivet i:Free Radic Biol Med
Main Authors: Yadav, Neelu, Kumar, Sandeep, Kumar, Rahul, Srivastava, Pragya, Sun, Leimin, Rapali, Peter, Marlowe, Timothy, Schneider, Andrea, Inigo, Joseph, O’Malley, Jordan, Londonkar, Ramesh, Gogada, Raghu, Chaudhary, Ajay, Yadava, Nagendra, Chandra, Dhyan
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734361/
https://ncbi.nlm.nih.gov/pubmed/26627937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.11.028
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