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Changes in expression of WT1 during induced differentiation of the acute myeloid leukemia cell lines by treatment with 5-aza-2′-deoxycytidine and all-trans retinoic acid

The aim of the present study was to investigate the effect of 5-aza-2′-deoxycytidine (decitabine; DAC) and all-trans retinoic acid (ATRA) on Wilms' tumor 1 (WT1) in acute myeloid leukemia (AML) in vitro. The methylation status of the WT1 promoter was analyzed using methylation-specific polymera...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: XIANG, LILI, ZHOU, JIAHE, GU, WEIYING, WANG, RONG, WEI, JIANG, QIU, GUOQIANG, CEN, JIANNONG, XIE, XIAOBAO, CHEN, ZIXING
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734319/
https://ncbi.nlm.nih.gov/pubmed/26893773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.4052
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