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The Impact of Side-chain Packing on Protein Docking Refinement

We study the impact of optimizing side-chain positions in the interface region between two proteins during the process of binding. Mathematically, the problem is similar to side-chain prediction, extensively explored in the process of protein structure prediction. The protein-protein docking applica...

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Detalhes bibliográficos
Publicado no:J Chem Inf Model
Main Authors: Moghadasi, Mohammad, Mirzaei, Hanieh, Mamonov, Artem, Vakili, Pirooz, Vajda, Sandor, Paschalidis, Ioannis Ch., Kozakov, Dima
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734134/
https://ncbi.nlm.nih.gov/pubmed/25714358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci500380a
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