Type I Interferon Response Limits Astrovirus Replication and Protects against Increased Barrier Permeability In Vitro and In Vivo

Little is known about intrinsic epithelial cell responses against astrovirus infection. Here we show that human astrovirus type 1 (HAstV-1) infection induces type I interferon (beta interferon [IFN-β]) production in differentiated Caco2 cells, which not only inhibits viral replication by blocking po...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Marvin, Shauna A., Huerta, C. Theodore, Sharp, Bridgett, Freiden, Pamela, Cline, Troy D., Schultz-Cherry, Stacey
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2016
Предметы:
Pathogenesis and Immunity
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733991/
https://ncbi.nlm.nih.gov/pubmed/26656701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02367-15
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы