Type I Interferon Response Limits Astrovirus Replication and Protects against Increased Barrier Permeability In Vitro and In Vivo

Little is known about intrinsic epithelial cell responses against astrovirus infection. Here we show that human astrovirus type 1 (HAstV-1) infection induces type I interferon (beta interferon [IFN-β]) production in differentiated Caco2 cells, which not only inhibits viral replication by blocking po...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Marvin, Shauna A., Huerta, C. Theodore, Sharp, Bridgett, Freiden, Pamela, Cline, Troy D., Schultz-Cherry, Stacey
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Pathogenesis and Immunity
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733991/
https://ncbi.nlm.nih.gov/pubmed/26656701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02367-15
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