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Prenatal Maternal Stress Predicts Methylation of Genes Regulating the Hypothalamic-Pituitary-Adrenocortical System in Mothers and Newborns in the Democratic Republic of Congo

Exposure to stress early in life permanently shapes activity of the hypothalamic-pituitary-adrenocortical (HPA) axis and the brain. Prenatally, glucocorticoids pass through the placenta to the fetus with postnatal impacts on brain development, birth weight, and HPA axis functioning. Little is known...

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Bibliographic Details
Published in:Child Dev
Main Authors: Kertes, Darlene A., Kamin, Hayley S., Hughes, David A., Rodney, Nicole C., Bhatt, Samarth, Mulligan, Connie J.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733886/
https://ncbi.nlm.nih.gov/pubmed/26822443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cdev.12487
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