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Bisphosphonate Treatment in Osteoporosis: Optimal Duration of Therapy and the Incorporation of a Drug Holiday

BACKGROUND: Bisphosphonates are the most widely used treatment for osteoporosis. They accumulate in the bone for years, and therefore, their inhibitory effects on osteoclasts may persist after drug discontinuation. The ideal duration of therapy remains controversial. QUESTIONS/PURPOSES: The purpose...

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Vydáno v:HSS J
Hlavní autoři: Villa, Jordan C., Gianakos, Arianna, Lane, Joseph M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733702/
https://ncbi.nlm.nih.gov/pubmed/26855630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11420-015-9469-1
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