Phospholipase A2 activity can protect renal tubules from oxygen deprivation injury.

During hypoxic or ischemic renal tubular injury, phospholipase A2 (PLA2) induces membrane deacylation, causing fatty acid accumulation and phospholipid breakdown. Because these changes can compromise cellular integrity, PLA2 activity has been widely proposed as a critical mediator of hypoxic renal t...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Zager, R A, Schimpf, B A, Gmur, D J, Burke, T J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47336/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8367497/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.17.8297
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