Vesicular Monoamine Transporter Protein Expression Correlates with Clinical Features, Tumor Biology, and MIBG Avidity in Neuroblastoma: A Report from the Children's Oncology Group

PURPOSE: Vesicular monoamine transporters 1 and 2 (VMAT1 and VMAT2) are thought to mediate MIBG uptake in adult neuroendocrine tumors. In neuroblastoma, the norepinephrine transporter (NET) has been investigated as the principal MIBG uptake protein, though some tumors without NET expression concentr...

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Pubblicato in:Eur J Nucl Med Mol Imaging
Autori principali: Temple, William, Mendelsohn, Lori, Kim, Grace E., Nekritz, Erin, Gustafson, W. Clay, Lin, Lawrence, Giacomini, Kathy, Naranjo, Arlene, Van Ryn, Collin, Yanik, Gregory A., Kreissman, Susan G., Hogarty, Michael, Matthay, Katherine K., DuBois, Steven G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733400/
https://ncbi.nlm.nih.gov/pubmed/26338179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-015-3179-2
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