Reducing Adiposity in a Critical Developmental Window Has Lasting Benefits in Mice

Although most adults can lose weight by dieting, a well-characterized compensatory decrease in energy expenditure promotes weight regain more than 90% of the time. Using mice with impaired hypothalamic leptin signaling as a model of early-onset hyperphagia and obesity, we explored whether this unfav...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Lerea, Jaclyn S., Ring, Laurence E., Hassouna, Rim, Chong, Angie C. N., Szigeti-Buck, Klara, Horvath, Tamas L., Zeltser, Lori M.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733128/
https://ncbi.nlm.nih.gov/pubmed/26587784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1753
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