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Epidermal growth factor receptor signaling regulates granulocyte-macrophage colony-stimulating factor production by airway epithelial cells and established allergic airway disease

BACKGROUND: Airway epithelial cells (AEC) are increasingly recognized as a major signaling center in the pathogenesis of allergic asthma. A previous study demonstrated that epithelial growth factor receptor (EGFR) signaling in AEC regulated key features of allergic airway disease. However, it is unc...

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Detalhes bibliográficos
Publicado no:Clin Exp Allergy
Main Authors: Acciani, Thomas H., Suzuki, Takuji, Trapnell, Bruce C., Cras, Timothy D. Le
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732899/
https://ncbi.nlm.nih.gov/pubmed/26263242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12612
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