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c-Jun N-terminal kinase inhibitor favors transforming growth factor-β to antagonize hepatitis B virus X protein-induced cell growth promotion in hepatocellular carcinoma

Transforming growth factor (TGF)-β induces cell growth arrest in well-differentiated hepatocellular carcinoma (HCC) while hepatitis B virus X protein (HBx) minimizes the tumor suppression of TGF-β signaling in early chronic hepatitis B. However, how to reverse the oncogenic effect of HBx and sustain...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: WU, YAN-HUI, AI, XI, LIU, FU-YAO, LIANG, HUI-FANG, ZHANG, BI-XIANG, CHEN, XIAO-PING
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732859/
https://ncbi.nlm.nih.gov/pubmed/26648552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4644
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