4-Phenylbutyrate protects rat skin flaps against ischemia-reperfusion injury and apoptosis by inhibiting endoplasmic reticulum stress

4-phenylbutyrate (4-PBA) is a low molecular weight fatty acid, which has been demonstrated to regulate endoplasmic reticulum (ER) stress. ER stress-induced cell apoptosis has an important role in skin flap ischemia; however, a pharmacological approach for treating ischemia-induced ER dysfunction has...

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Veröffentlicht in:Mol Med Rep
Hauptverfasser: YUE, ZHEN-SHUANG, ZENG, LIN-RU, QUAN, REN-FU, TANG, YANG-HUA, ZHENG, WEN-JIE, QU, GANG, XU, CAN-DA, ZHU, FANG-BING, HUANG, ZHONG-MING
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2016
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732847/
https://ncbi.nlm.nih.gov/pubmed/26648447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4636
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