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p53 causes butein-mediated apoptosis of chronic myeloid leukemia cells

Progression of chronic myeloid leukemia, marked by the oncogenic Bcr-Abl mutation, is tightly associated with an alteration of the p53 pathway. It is known that butein extracted from various plants represses cancer growth. Although the anticancer effects of butein are widely accepted, the mechanisms...

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Dades bibliogràfiques
Publicat a:Mol Med Rep
Autors principals: WOO, SANG-MI, CHOI, YOUN KYNUG, KIM, AH JEONG, CHO, SUNG-GOOK, KO, SEONG-GYU
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732842/
https://ncbi.nlm.nih.gov/pubmed/26676515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4672
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