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Harnessing the power of the immune system via blockade of PD-1 and PD-L1: a promising new anticancer strategy

Cancer cells employ several mechanisms to evade the immune system of their host, thus escaping immune recognition and elimination. Of particular interest is a cancer cell’s ability to co-opt the immune system’s innate ligands and inhibitory receptors (also known as checkpoints), thus creating an imm...

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Detalhes bibliográficos
Publicado no:Immunotherapy
Main Authors: Reiss, Kim A, Forde, Patrick M, Brahmer, Julie R
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732706/
https://ncbi.nlm.nih.gov/pubmed/24815784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.14.9
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