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Glutamate Dehydrogenase Is Required by Mycobacterium bovis BCG for Resistance to Cellular Stress

We recently reported on our success to generate deletion mutants of the genes encoding glutamate dehydrogenase (GDH) and glutamine oxoglutarate aminotransferase (GOGAT) in M. bovis BCG, despite their in vitro essentiality in M. tuberculosis. We could use these mutants to delineate the roles of GDH a...

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Pubblicato in:PLoS One
Autori principali: Gallant, James L., Viljoen, Albertus J., van Helden, Paul D., Wiid, Ian J. F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732601/
https://ncbi.nlm.nih.gov/pubmed/26824899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147706
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