Clarithromycin in GABA-related Hypersomnolence: A Randomized, Crossover Trial

OBJECTIVE: Some central hypersomnolence syndromes are associated with a positive allosteric modulator of GABA-A receptors in cerebrospinal fluid. Negative allosteric modulators of GABA-A receptors, including clarithromycin, have been reported to reduce sleepiness in these patients. We sought to syst...

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Vydáno v:Ann Neurol
Hlavní autoři: Trotti, Lynn Marie, Saini, Prabhjyot, Bliwise, Donald L., Freeman, Amanda A., Jenkins, Andrew, Rye, David B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732573/
https://ncbi.nlm.nih.gov/pubmed/26094838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24459
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