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The Cellular Apoptosis Susceptibility Protein (CAS) Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis and Cell Proliferation

A signature event during the cell intrinsic apoptotic pathway is mitochondrial outer membrane permeabilization, leading to formation of the apoptosome, a caspase activation complex. The cellular apoptosis susceptibility protein (CAS) can facilitate apoptosome assembly by stimulating nucleotide excha...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Monian, Prashant, Jiang, Xuejun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732220/
https://ncbi.nlm.nih.gov/pubmed/26668314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.685008
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