Failure of a heterologous recombinant Sca5/OmpB protein-based vaccine to elicit effective protective immunity against Rickettsia rickettsii infections in C3H/HeN mice

Spotted fever group (SFG) rickettsial species are obligate intracellular tick-borne pathogens that are responsible for important human diseases. Previous reports have demonstrated the feasibility of using recombinant surface cell antigen Sca5/OmpB to elicit protective immunity against homologous cha...

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Enregistré dans:
Détails bibliographiques
Publié dans:Pathog Dis
Auteurs principaux: Riley, Sean P., Cardwell, Marissa M., Chan, Yvonne G.Y., Pruneau, Ludovic, Del Piero, Fabio, Martinez, Juan J.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732028/
https://ncbi.nlm.nih.gov/pubmed/26519448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftv101
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