Double-blind, placebo-controlled, proof-of-concept trial of bexarotene Xin moderate Alzheimer’s disease

BACKGROUND: We assessed the impact of retinoid X receptor (RXR) agonist bexarotene on brain amyloid measured by amyloid imaging in patients with Alzheimer’s disease (AD) in a proof-of-concept trial. METHODS: Twenty patients with AD [Mini Mental State Examination (MMSE) score 10–20 inclusive] with po...

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Publicado en:Alzheimers Res Ther
Main Authors: Cummings, Jeffrey L., Zhong, Kate, Kinney, Jefferson W., Heaney, Chelcie, Moll-Tudla, Joanne, Joshi, Abhinay, Pontecorvo, Michael, Devous, Michael, Tang, Anne, Bena, James
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731943/
https://ncbi.nlm.nih.gov/pubmed/26822146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-016-0173-2
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