White and gray matter damage in primary progressive MS: The chicken or the egg?

OBJECTIVE: The temporal relationship between white matter (WM) and gray matter (GM) damage in vivo in early primary progressive multiple sclerosis (PPMS) was investigated testing 2 hypotheses: (1) WM tract abnormalities predict subsequent changes in the connected cortex (“primary WM damage model”);...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Bodini, Benedetta, Chard, Declan, Altmann, Daniel R., Tozer, Daniel, Miller, David H., Thompson, Alan J., Wheeler-Kingshott, Claudia, Ciccarelli, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731689/
https://ncbi.nlm.nih.gov/pubmed/26674332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002237
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