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Anti-inflammatory and anti-apoptotic effects of oxysophoridine on lipopolysaccharide-induced acute lung injury in mice

Oxysophoridine (OSR) is an alkaloid with multiple pharmacological activities. This study aimed to investigate the protective effects and underlying mechanisms of OSR on lipopolysaccharide (LPS)-induced acute lung injury (ALI) in mice. Here, we found that OSR treatment markedly mitigated LPS-induced...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Transl Res
Hauptverfasser: Fu, Junjing, Wang, Yongtao, Zhang, Jianxin, Wu, Wei, Chen, Xiyan, Yang, Yanrong
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731665/
https://ncbi.nlm.nih.gov/pubmed/26885265
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