Preclinical evaluation of afatinib (BIBW2992) in esophageal squamous cell carcinoma (ESCC)

Esophageal squamous cell carcinoma (ESCC) is the eighth most common cancer worldwide. Epidermal growth factor receptors (EGFR) are often overexpressed in esophageal cancers, thus anti-EGFR inhibitors have been evaluated in ESCC. Afatinib was an irreversible inhibitor of these ErbB family receptors....

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Bibliographic Details
Published in:Am J Cancer Res
Main Authors: Wong, Chi Hang, Ma, Brigette Buig Yue, Hui, Connie Wun Chun, Tao, Qian, Chan, Anthony Tak Cheung
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731633/
https://ncbi.nlm.nih.gov/pubmed/26885448
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