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Mild KCC2 Hypofunction Causes Inconspicuous Chloride Dysregulation that Degrades Neural Coding
Disinhibition caused by Cl(−) dysregulation is implicated in several neurological disorders. This form of disinhibition, which stems primarily from impaired Cl(−) extrusion through the co-transporter KCC2, is typically identified by a depolarizing shift in GABA reversal potential (E(GABA)). Here we...
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| Publicado no: | Front Cell Neurosci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731508/ https://ncbi.nlm.nih.gov/pubmed/26858607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00516 |
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