IGF-Binding Proteins in Type-1 Diabetes Are More Severely Altered in the Presence of Complications

AIMS: Reduced levels of free and total insulin-like growth factor 1 (IGF-I) have been observed in type-1 diabetes (T1D) patients. The bioavailability of IGF-I from the circulation to the target cells is controlled by multifunctional IGF-binding proteins (IGFBPs). The aim of this study was to profile...

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Publicado en:Front Endocrinol (Lausanne)
Autores principales: Sharma, Ashok, Purohit, Sharad, Sharma, Shruti, Bai, Shan, Zhi, Wenbo, Ponny, Sithara Raju, Hopkins, Diane, Steed, Leigh, Bode, Bruce, Anderson, Stephen W., She, Jin-Xiong
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
Materias:
Endocrinology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731488/
https://ncbi.nlm.nih.gov/pubmed/26858687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2016.00002
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