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Identification of significantly mutated regions across cancer types highlights a rich landscape of functional molecular alterations
Cancer sequencing studies have primarily identified cancer-driver genes by the accumulation of protein-altering mutations. An improved method would be annotation-independent, sensitive to unknown distributions of functions within proteins, and inclusive of non-coding drivers. We employed density-bas...
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| I publikationen: | Nat Genet |
|---|---|
| Huvudupphovsmän: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731297/ https://ncbi.nlm.nih.gov/pubmed/26691984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3471 |
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