Thalidomide Improves the Intestinal Mucosal Injury and Suppresses Mesenteric Angiogenesis and Vasodilatation by Down-Regulating Inflammasomes-Related Cascades in Cirrhotic Rats

BACKGROUND AND AIMS: By blocking TNFα-related effects, thalidomide not only inhibits hepatic fibrogenesis but improves peripheral vasodilatation and portal hypertension in cirrhotic rats. Nonetheless, the investigation of thalidomide's effects on splanchnic and collateral microcirculation has b...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Li, Tzu-Hao, Huang, Chia-Chang, Yang, Ying-Ying, Lee, Kuei-Chuan, Hsieh, Shie-Liang, Hsieh, Yun-Cheng, Alan, Lin, Lin, Han-Chieh, Lee, Shou-Dong, Tsai, Chang-Youh
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731147/
https://ncbi.nlm.nih.gov/pubmed/26820153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147212
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