Involvement of TRPV4 in serotonin-evoked scratching

Several thermo-sensitive TRP channels (TRPV1, -3; TRPA1) have been implicated in itch. In contrast, the role of transient receptor potential vanilloid type-4 (TRPV4) in itch is unknown. Therefore, we investigated if TRPV4, a temperature-sensitive cation channel, plays an important role in acute itch...

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Veröffentlicht in:J Invest Dermatol
Hauptverfasser: Akiyama, Tasuku, Ivanov, Margaret, Nagamine, Masaki, Davoodi, Auva, Carstens, Mirela Iodi, Ikoma, Akihiko, Cevikbas, Ferda, Kempkes, Cordula, Buddenkotte, Joerg, Steinhoff, Martin, Carstens, E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731048/
https://ncbi.nlm.nih.gov/pubmed/26763435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/JID.2015.388
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