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Redox State of Flavin Adenine Dinucleotide Drives Substrate Binding and Product Release in Escherichia coli Succinate Dehydrogenase

The Complex II family of enzymes, comprising the respiratory succinate dehydrogenases and fumarate reductases, catalyze reversible interconversion of succinate and fumarate. In contrast to the covalent flavin adenine dinucleotide (FAD) cofactor assembled in these enzymes, the soluble fumarate reduct...

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Publicat a:Biochemistry
Autors principals: Cheng, Victor W.T., Piragasam, Ramanaguru Siva, Rothery, Richard A., Maklashina, Elena, Cecchini, Gary, Weiner, Joel H.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731035/
https://ncbi.nlm.nih.gov/pubmed/25569225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501350j
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