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Super-resolution microscopy reveals altered desmosomal protein organization in pemphigus vulgaris patient tissue

Pemphigus vulgaris (PV) is an autoimmune epidermal blistering disease in which autoantibodies (IgG) are directed against the desmosomal cadherin desmoglein 3 (Dsg3). In order to better understand how PV IgG alters desmosome morphology and function in vivo, PV patient biopsies were analyzed by struct...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Stahley, Sara N., Warren, Maxine F., Feldman, Ron J., Swerlick, Robert A., Mattheyses, Alexa L., Kowalczyk, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730957/
https://ncbi.nlm.nih.gov/pubmed/26763424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/JID.2015.353
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