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Super-resolution microscopy reveals altered desmosomal protein organization in pemphigus vulgaris patient tissue

Pemphigus vulgaris (PV) is an autoimmune epidermal blistering disease in which autoantibodies (IgG) are directed against the desmosomal cadherin desmoglein 3 (Dsg3). In order to better understand how PV IgG alters desmosome morphology and function in vivo, PV patient biopsies were analyzed by struct...

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Détails bibliographiques
Publié dans:J Invest Dermatol
Auteurs principaux: Stahley, Sara N., Warren, Maxine F., Feldman, Ron J., Swerlick, Robert A., Mattheyses, Alexa L., Kowalczyk, Andrew P.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730957/
https://ncbi.nlm.nih.gov/pubmed/26763424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/JID.2015.353
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