Eosinophil localization to the basement membrane zone is autoantibody- and complement-dependent in a human cryosection model of bullous pemphigoid

Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by antibodies (IgG and IgE) targeting cell-substrate adhesion proteins. A variety of BP models suggest that autoantibody-dependent neutrophil degranulation is essential for blister formation. However, lesional biopsies reveal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Exp Dermatol
Egile Nagusiak: Messingham, Kelly N., Wang, Jeffrey W., Holahan, Heather M., Srikantha, Rupasree, Aust, Samantha C., Fairley, Janet A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730885/
https://ncbi.nlm.nih.gov/pubmed/26475989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/exd.12883
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